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Why are most therapeutic drugs unable to cross the blood brain barrier? What strategies are being used to make penetration of the blood brain barrier possible?

What determines the speed at which a drug crosses the blood brain barrier? Is this related to a drug’s potency or affinity or addictive properties? Choose any (one) psychoactive drug (e.g., LSD, magic mushrooms, Marijuana, cocaine, heroin, etc.) and describe it’s mechanism of action in the brain. According to the information you now have learned about how drugs effect the brain, is drug addiction a choice or a disease?

Elaborate on this topic in your discussion.

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